Skripsi

AKTIVITAS SENYAWA ANTIBAKTERI DAUN SENDUDUK (Melastoma malabathricum L.) PADA BAKTERI Escherichia coli ATCC 25922 dan Staphylococcus aureus ATCC 25923

---

Penilaian

---

Infectious diseases such as diarrhea caused by Escherichia coli and Staphylococcus aureus bacteria become a problem because in the use of antibiotics that are widespread and improperly can cause resistance properties, so it is necessary to search for new antibacterial compounds by utilizing plants that are antibacterial. One of them is Senduduk plants (Melastoma malabathricum L). This study aims to determine fraction that have antibacterial activity of senduduk leaves, obtain antibacterial compounds, compounds groups, and determine the Minimum Inhibitory Concentration (MIC) of compounds from the active fraction of senduduk leaf extract in bacteria E. coli and S. aureus. Antibacterial activity test and determination of minimum inhibitory concentration (MIC) by agar diffusion method. The test bacteria used were E. coli and S. aureus. The results showed that the active fraction of the Senduduk leaves methanol extract was the ethyl acetate fraction and the methanol fraction. The active compound group which has antibacterial activity in the ethyl acetate fraction isolate E7.22 is the flavonoid compound with Rf value of 0.53 cm and isolate E11 is tannin compound with Rf value of 0.4 cm. Minimum Inhibitory Concentration (MIC) of active compound of ethyl acetate fraction of Senduduk leaves isolate E7.22 and E11 in E. coli and S. aureus at concentration of 500 μg / ml classified as having moderate antibacterial compounds. Keywords: Escherichia coli, Staphylococcus aureus, Active Fraction, Active Compouds, MIC

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2007001847	T32195	T321952020	Central Library (REFERENCES)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T321952020

Publisher

Inderalaya : Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2020

Collation

xix, 55 hlm. : ilus. ; 28 cm

Language

Indonesia

ISBN/ISSN

-

Classification

547.707

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

-

Subject(s)

Jurusan Biologi
Antibakteri-Daun Senduduk

Specific Detail Info

-

Statement of Responsibility

DS

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment