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POTENSI EKSTRAK ETANOL BIJI JENGKOL (Archidendron jiringa) SEBAGAI ANTIHIPERLIPIDEMIA PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI PAKAN TINGGI LEMAK DAN PROPILTIOURASIL

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Jengkol seed (Archidendron jiringa) contains of secondary metabolite such as flavonoids, alkaloids, tannins, saponins, phenolics and triterpenoids that have the potential as antihyperlipidemia. This study aims to determine the characteristics and effects of ethanol extract of jengkol seeds to decrease total cholesterol, LDL and triglyceride levels. Test animals test are divided into 5 groups which are positive control group (Simvastatin 0.987 mg/KgBB), negative control group (0.5% NaCMC) and ethanol extract jengkol seed treatment group (Doses 250, 750 and 1000 mg/kgBW). Rats have induced with high-fat feed and propylthiouracil, then have given a test preparation for 14 days after induction. The results showed that ethanol extract of jengkol seeds at a dose of 1000 mg/kgBW could significantly decreased total cholesterol, LDL and triglyceride levels by 53.25 ± 6.65 mg/dL, 19.95 ± 1.39 mg/dL and 69, 07 ± 1.40 mg/dL. The result showed that ethanol extract of jengkol seeds has activity as an antihyperlipidemia and there is a significant difference compared to the negative control group (p

Availability
Inventory Code Barcode Call Number Location Status
2007001814T32697T326972020Central Library (REFERENCES)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T326972020
Publisher
Inderalaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya.,
Collation
xix, 103 hlm. : ilus. ; 28 cm
Language
Indonesia
ISBN/ISSN
-
Classification
547.207
Content Type
Text
Media Type
unmediated
Carrier Type
-
Edition
-
Subject(s)
Jurusan Farmasi
Reaksi Kimia Organik-Ekstrak Etanol Biji Jengkol
Specific Detail Info
-
Statement of Responsibility
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No other version available

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