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PENGARUH PEMBERIAN EKSTRAK IKAN PATIN SIAM TERHADAP SEL FIBROBLAS PASCA EKSTRAKSI GIGI TIKUS WISTAR

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Background: Tooth extraction is a common treatment procedure that result in the formation of wound. Nutrition is one of the factors that influence wound healing. Siamese catfish is a source of nutrition, but its effect in wound healing process is still unknown. Objective: To determine the effect of administration of Siamese catfish extract orally on the number of fibroblast cells in wound healing after tooth extraction of Wistar rats. Methods: This research was true experimental laboratory with posttest only control group design. 24 male Wistar rat were divided into 6 groups. After the mandibular left incisor was extracted, rats in groups 1, 2, and 3 were given Siamese catfish extract and groups 4, 5, and 6 were given aquadest orally once a day. Groups 1 and 4 were treated for 3 days, groups 2 and 5 were treated for 5 days, and groups 3 and 6 were treated for 7 days, then the rats were euthanized and made histological preparations. Fibroblast cells were calculated using Image Raster software and analyzed using One Ways ANOVA and Post Hoc LSD tests. Results: The number of fibroblast cells increased on the the 5th day and reached the highest number on the 7th day. ANOVA test showed a significant difference in the mean of fibroblast number between the treatment and control groups (p0,05) between Siamese catfish extract and aquadest groups on the 3rd day. Conclusion: The administration of Siamese catfish extract orally can increase the number of fibroblast cells in wound healing after tooth extraction of Wistar rats.

Availability
Inventory Code Barcode Call Number Location Status
2007000539T40050T40050Central Library (REFERENCES)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T40050
Publisher
Palembang : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya.,
Collation
xv, 71 hlm.: Ilus., tab.; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
617.640 7
Content Type
Text
Media Type
unmediated
Carrier Type
unspecified
Edition
-
Subject(s)
Penyembuhan Luka
Kedokteran Gigi dan Mulut
Specific Detail Info
-
Statement of Responsibility
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