Skripsi

HUBUNGAN AWITAN PREEKLAMPSIA DENGAN LUARAN MATERNAL DAN PERINATAL DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE TAHUN 2019-2020

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Penilaian

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Background. Preeclampsia is defined as a syndrome that is unique to pregnancy, characterized by new-onset hypertension beginning ≥20 weeks of gestation and proteinuria. As a syndrome, it is also related to many organ systems. Based on the onset and the underlying pathophysiology, preeclampsia is classified into two subtypes: early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE). EO-PE is less prevalent but it is associated with increased risk of adverse maternal and perinatal outcomes to a greater degree than LO-PE. This study aimed to assess the relation between the onset of preeclampsia with maternal and perinatal outcomes at Dr. Mohammad Hoesin Central Hospital in Palembang. Methods. A cross sectional study was conducted among pregnant women with preeclampsia who gave birth at Dr. Mohammad Hoesin Central Hospital, a tertiary care facility in Palembang on July 2019-July 2020. The data was collected by using medical records. Total sampling was chosen as the sampling technique. Descriptive statistics, both univariate and bivariate, were performed first, then the data was analyzed by binary logistic regression to account for the relation between the onset of preeclampsia with maternal and perinatal outcomes. Results. Showed 212 preeclamptic mothers, 82 (38.7%) cases were early-onset preeclampsia (EO-PE) and the rest 130 (61.3%) cases were late-onset preeclampsia (LO-PE). The EO-PE group had higher risk of developing HELLP syndrome (OR=4.919, p-value 0.000), SGA (OR= 4.919, p-value 0.000), LBW (OR= 14.265, p-value 0.000), asphyxia (OR= 3.226, p-value 0.001), and perinatal death (OR= 19.147, p-value 0.000) compared to the LO-PE group. Meanwhile, the relation between the onset of preeclampsia with eclampsia (OR= 2.305, p-value 0.073), placental abruption (OR= 3.951, p-value 0.051), pulmonary edema (OR= 2.430, p-value 0.337), multiple organ failure (OR= 2.940, p-value 0.094), postpartum hemorrhage (OR= 0.309, p-value 0.287), and maternal death (OR= 0.790, p-value 0.848) didn’t reveal statistically significant. Conclusion. The study findings indicate that for some maternal and perinatal outcomes, women with EO-PE had a significantly higher risk for adverse outcomes than those with LO-PE. Keywords: Early-onset preeclampsia, EO-PE, Late-onset preeclampsia, EO-PE, Maternal Outcome, Perinatal Outcome

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2007000507	T39647	T396472020	Central Library (REFERENCES)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T396472020

Publisher

Palembang : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2020

Collation

xviii, 142 hlm.: Ilus., tab.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

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Content Type

Text

Media Type

unmediated

Carrier Type

unspecified

Edition

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Subject(s)

Kedokteran
Gangguan Reproduksi

Specific Detail Info

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Statement of Responsibility

HALIM

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