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Image of Isolasi senyawa turunan asilfloroglusinol dari ekstrak metanol buah karamunting (rhodomyrtus tomentosa) dan uji sitotoksik terhadap sel murin leukemia p-388

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Isolasi senyawa turunan asilfloroglusinol dari ekstrak metanol buah karamunting (rhodomyrtus tomentosa) dan uji sitotoksik terhadap sel murin leukemia p-388

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Telah dilakukan isolasi senyawa turunan asilfloroglusinol dari ekstrak metanol buah karamunting (Rhodomyrtus tomentosa). Ekstraksi dilakukan dengan metode maserasi sedangkan pemisahan dan pemurnian metabolit sekunder dilakukan dengan berbagai teknik kromatografi. Senyawa hasil isolasi diperoleh berupa padatan kuning dengan titik leleh 118oC – 200oC. Berdasarkan analisa data spektrum, IR, 1H-NMR, 13C-NMR, HMQC, HMBC serta perbandingan dengan data literatur, disimpulkan bahwa senyawa hasil isolasi adalah turunan asilfloroglusinol yaitu rhodomyrton. Senyawa rhodomyrton dikategorikan sangat aktif sitotoksik terhadap sel murin leukemia P-388 dengan nilai IC50 sebesar 0,12 μg/mL.


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Detail Information
Series Title
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Call Number
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Publisher
Inderalaya : ., 2016
Collation
xvi, 41 hlm. : ilus.
Language
Indonesia
ISBN/ISSN
-
Classification
NONE
Content Type
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Media Type
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Carrier Type
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Edition
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Subject(s)
asilfloroglusinol
Karamunting (Rhodomyrtus tomentosa)
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Statement of Responsibility
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