Skripsi

STANDARDISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU IRENG (Curcuma aeruginosa Roxb.) PADA TIKUS PUTIH (Rattus norvegicus) BETINA GALUR WISTAR

---

Penilaian

---

Temu ireng (Curcuma aeruginosa Roxb.) is one of the medicinal plants that has been reported to have antioxidant, antibacterial, anti-inflammatory, and hepatoprotector activities, but this plant has not been widely studied regarding its toxicity. This study conducted an acute toxicity test of ethanol extract of temu ireng rhizome against female Wistar strain rats using the Acute Toxic Class method. The results of standardization of ethanol extracts of temu ireng rhizomes show thick, dark brown extracts and have a distinctive odor of extracts, water soluble juice content 43.33 ± 5.77; ethanol soluble juice content 83.33 ± 11.54; moisture content 6.67 ± 1.15; total ash content 12.33 ± 0.76; acid insoluble ash content 0.51 ± 0.28 and specific gravity 1.03 ± 0.01 (mg/dL). Toxicity observations showed that death and toxic symptoms occurred in the test animals. There was no change in body weight of rats between before and after administration of the extract (p>0.05). In the examination of biochemical parameters, there were no significant differences (p>0.05) between the normal and treatment groups, while the levels of SGOT and SGPT had significant differences (p

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2407004257	T150496	T1504962024	Central Library (Reference)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T1504962024

Publisher

Indralaya : Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2024

Collation

xv, 46 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

-

Classification

615.321 07

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

-

Subject(s)

Prodi Farmasi
Rimpang Temu Ireng

Specific Detail Info

-

Statement of Responsibility

KA

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment