Skripsi

EFEKTIVITAS ANTIBAKTERI KITOSAN CANGKANG KEPITING BAKAU (SCYLLA SERRATA) TERHADAP STREPTOCOCCUS MUTANS

---

Penilaian

---

Background: Streptococcus mutans is the primary bacterium responsible for dental caries. One potential natural antibacterial agent is chitosan, which is derived from the shells of mangrove crabs (Scylla serrata). Chitosan has the ability to inhibit bacterial growth and induce bacterial cell death. Objective: To determine the antibacterial effectiveness of chitosan from mangrove crab (Scylla serrata) shell against Streptococcus mutans bacteria. Methods: An in vitro laboratory experimental design with a post-test-only control group was used. The study tested the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and inhibition zone of chitosan at concentrations of 1%, 0.5%, 0.25%, and 0.125%, with 0.2% chlorhexidine as a positive control and distilled water as a negative control. Each treatment was repeated four times. The MIC was determined using the broth dilution method, MBC with the agar dilution method, and the inhibition zone with the disc diffusion method. Results: The MIC was achieved at a concentration of 0.5%, while the MBC was not achieved even at a concentration of 1%. Inhibition zones were formed at 1% concentration with an average diameter of 0.32 mm and at 0.5% concentration with 0.28 mm. Conclusion: Chitosan derived from mangrove crab shells demonstrated antibacterial activity against Streptococcus mutans. however, its effectiveness was relatively low and not comparable to the positive control.

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2507004089	T1781982	T1781982025	Central Library (REFERENCE)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T1781982025

Publisher

Indralaya : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya., 2025

Collation

xxii, 549 hlm.; ilus.; tab.; 29 cm.

Language

Indonesia

ISBN/ISSN

-

Classification

611.607

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Gigi dan Mulut

Specific Detail Info

-

Statement of Responsibility

TUTI

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment