Skripsi

STUDI INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI GERIATRI DI RSUD SITI FATIMAH PROVINSI SUMATERA SELATAN

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Penilaian

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Hypertension is one of the most common diseases in geriatric patients. The use of various antihypertensive drugs can increase the risk of drug interactions. Drug interactions occur when two or more drugs are given simultaneously, so that they affect each other and have the potential to cause undesirable effects. The purpose of this study was to identify patterns of antihypertensive drug interactions and analyze the severity of drug interactions in geriatric hypertensive patients at Siti Fatimah Hospital, South Sumatra Province in 2025. The study was conducted prospectively with a purposive sampling technique. Analysis of drug interactions by assessing patients, reviewing drugs related to patient conditions, and reviewing literature. The results showed that the most patients were female, reaching 57% of hypertension cases found in the elderly age group (60-74 years). All geriatric hypertensive patients who were hospitalized experienced the most comorbidities in coronary heart disease (23.2%). The profile of antihypertensive types shows that the three most widely used antihypertensive groups are Calcium Channel Blockers (33%), Angiotensin Receptor Blockers (29%), diuretics (28%), temporary Beta Blockers (10%). Antihypertensive drug interactions in hospitalized geriatric patients most often occur in the combination of bisoprolol and amlodipine (64%), dominated by pharmacodynamic mechanisms. Keywords: Drug interactions, geriatric patients, antihypertensive therapy.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2507002902	T173570	T1735702025	Central Library (REFERENCE)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1735702025

Publisher

Indralaya : ., 2025

Collation

xi, 80 hlm.; tab.; 29 cm.

Language

Indonesia

ISBN/ISSN

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Classification

615.107

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Kimia Farmasi

Specific Detail Info

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Statement of Responsibility

TUTI

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