Skripsi

PERBANDINGAN METODE KATO-KATZ DENGAN PCR UNTUK MENDIAGNOSIS INFEKSI SOIL TRANSMITTED HELMINTHS

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Penilaian

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Soil-Transmitted Helminth (STH) infections are a public health problem in many developing countries, particularly in subtropical and tropical regions, including Indonesia. Intestinal parasite are among the most common infections affecting individuals with HIV due to compromised immune function. Accurate diagnostic methods are essential for proper detection of these infections. This study aimed to compare the accuracy of the Kato-Katz method and PCR in diagnosing STH infections among HIV patients in Palembang, Indonesia. This observational cross-sectional study involved 34 HIV-positive subjects. Stool samples from each participant were examined using both Kato-Katz and PCR methods. Data were analyzed using diagnostic test parameters, and Kappa test. The prevalence of STH infection detected by the Kato-Katz method was 94.12%, while the PCR method detected 70.59%. Kato-Katz identified only Ascaris lumbricoides, whereas PCR detected Ascaris lumbricoides, Necator americanus, and including mixed infections. The sensitivity of PCR was 71.90%, specificity 50.00%, positive predictive value (PPV) 95.88%, negative predictive value (NPV) 10.00%, and diagnostic accuracy 70.58%. The agreement between methods was very weak, as shown by a low Kappa value 0,761. PCR was sensitive in detecting STH infections, particularly in cases of light or mixed infections, but it has limitations in identifying negative cases. A combination of Kato-Katz and PCR is recommended to achieve more accurate diagnostic results, especially in immunocompromised populations such as people living with HIV. Keywords: Soil-Transmitted Helminths, HIV, Kato-Katz, PCR, parasitic diagnosis

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2507003389	T173689	T1736892025	Central Library (Reference)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1736892025

Publisher

Palembang : Prodi Magister Ilmu Biomedik, Fakultas Kedokteran Universitas Sriwijaya., 2025

Collation

xviii, 120 hlm., ilus., tab.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

610.280 7

Content Type

Text

Media Type

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Carrier Type

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Edition

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Subject(s)

Ilmu Biomedik

Specific Detail Info

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Statement of Responsibility

MI

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