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UJI AKTIVITAS ANTIBAKTERI LOTION DARI HASIL FERMENTASI LIMBAH KULIT NANAS (ANANAS COMOSUS L) DAN KULIT JERUK (CITRUS SINENSIS) TERHADAP BAKTERI STAPHYLOCOCCUS EPIDERMIDIS

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Lotion was a practical and easy-to-use alternative for preventing infections from various skin diseases. One of the alternative ingredients with potential antibacterial properties to address Staphylococcus epidermidis bacterial infections was orange peel and pineapple peel. This study aimed to create a lotion with different variations of fermentation product concentrations (1%, 5%, 10%, and 15%) as an antibacterial agent against Staphylococcus epidermidis. The lotion evaluation tests included organoleptic testing, pH, viscosity, spreading power, adhesion, irritation, and stability (cycling test). Data analysis using SPSS revealed that the best lotion formula was formula 3 with a 10% fermentation product concentration, which had a slightly thick, slightly watery texture, a yellowish color, a characteristic citrus scent, was homogeneous, had a pH of 5.10, viscosity of 6,220 cP, spreading power of 6.30 cm, adhesion time of 6.44 s, no irritation, and stability during storage. Antibacterial activity using the well diffusion method resulted in an inhibition zone diameter of 11.16 ± 3.61mm. The minimum inhibitory concentration (MIC) of the fermentation product lotion was 50% ppm, and the control comparison for the fermentation product was at a concentration of 40%. Formula 3 lotion exhibited the best characterization and strong antibacterial activity against Staphylococcus epidermidis.

Availability
Inventory Code Barcode Call Number Location Status
2507000975T166451T1664512025Central Library (Reference)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T1664512025
Publisher
: Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya.,
Collation
xiii, 146 hlm.: ilus., tab.; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
615.407
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Farmasi
Specific Detail Info
-
Statement of Responsibility
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