Skripsi

SOLASI SENYAWA METABOLIT SEKUNDER TURUNAN FENOLIK DARI FRAKSI ETIL ASETAT BATANG MURBEI PUTIII (Morus alba L.)

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Penilaian

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Morus alba L. is a plant from Moraceae family which is found in tropical and subtropical areas. M. alba plant was reported to have displayed several bioactivities such as antioxidant, antitumor, antibacterial, anticancer, antidiabetic, and anti-inflammatory. M. alba plant has a diversity of secondary metabolites. This research was aimed to isolate and identify secondary metabolite compounds from ethyl acetate fraction of M. alba stem. The isolation process was done using maceration method with methanol as the solvent. The methanol crude extract was partitioned using liquid-liquid partition with n-hexane and ethyl acetate. Ethyl acetate fraction was separated by several chromatography techniques such as vacuum liquid chromatography, radial chromatography, flash column chromatography, and sephadex gravitation (LH-20). Identification of isolated compounds was carried out based on UV and NMR spectroscopic data (1H-NMR and TOCSY). The isolated compound was a reddish brown solid (4.5 mg).The UV spectra shows that the isolated compound was a phenolic compound without the ortho-dihydroxy groups because there was no bathochromic shift affect due to the addition of the AlCl3. 1H-NMR spectrum showed the presence of 2 aromatic ring units and 1 trans-vinyllic unit. Based on these data, the isolated compound was (E)-4-(3,5-dihydroxylstyryl)benzene-1,3-diol or oxyresvaratrol. This compound was a stilbene and had been reported previously from the ethyl acetate fraction of M. alba stem.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2407001172	T139576	T1395762024	Central Library (References)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1395762024

Publisher

Inderalaya : Prodi Ilmu Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2024

Collation

xv, 47 hlm.; ilus.; tab.; 21 cm.

Language

Indonesia

ISBN/ISSN

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Classification

582.120 7

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Prodi Ilmu Kimia
Murbei Putih--Tanaman Obat

Specific Detail Info

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Statement of Responsibility

MI

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