Image of UJI POTENSI IMUNOMODULATOR PADA MENCIT (MUS MUSCULUS) DAN ANTI PROLIFERASI SACCHAROMYCES CEREVISIAE DARI EKSTRAK METANOL DAUN SUNGKAI (PERONEMA CANESCENS JACK)

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UJI POTENSI IMUNOMODULATOR PADA MENCIT (MUS MUSCULUS) DAN ANTI PROLIFERASI SACCHAROMYCES CEREVISIAE DARI EKSTRAK METANOL DAUN SUNGKAI (PERONEMA CANESCENS JACK)

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Sungkai (Peronema canescens Jack.) is one of woody plants which is usually found in the Southern part of Sumatra which is often used as an herbal plant by people for flu and fever. This research was aimed to know immunomodulator potency of Sungkai in mice (Mus muculus) and effect extract to proliferation of Saccharomyces cerevisiae yeast and leukocytes. Yeast proliferation is associated with inflammatory activity while leukocytes assay is associated closely with immunostimulatory activity. Sungkai leaf was macerated using methanol then evaporated and tested for its phytochemistry profile and thin layer chromatography. Several compound groups were detected in phytochemistry profiling, such as terpene, steroid, alkaloid, saponin, and flavone. For the leukocytes assay of the extract, mice were used. There were several variables, positive control (Stimuno), negative control (CMC-Na), 5% concentration, 10% concentration, and 15% concentration. Mice leukocytes were taken from tail biopsy and counted under haemocytometer and microscope. 15% concentration extract results in the highest content of leukocytes found in the mice tail which was 9560 units. This indicated that sungkai extract has potency as immunomodulator as was tested with p0.05) cell growth among in the absence and in the presence of various concentrations of extract. This indicated that sungkai has no effect for the proliferation of S.cerevisiae cell.

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Inventory Code Barcode Call Number Location Status
2407000951T139256T1392562024Central Library (References)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T1392562024
Publisher
Inderalaya : Prodi Ilmu Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam.,
Collation
xvi, 35 hlm.; tab.; 21 cm.
Language
Indonesia
ISBN/ISSN
-
Classification
582.120 7
Content Type
Text
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Prodi Ilmu Kimia
Imunomodulator pada Mencit, Tanaman Obat
Specific Detail Info
-
Statement of Responsibility
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