Skripsi

AKTIVITAS ANTIBAKTERI KOMBINASI MINYAK LARVA BSF DAN MINYAK IKAN TUNA TERHADAP BAKTERI Staphylococcus aureus SECARA IN VITRO

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Penilaian

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Staphylococcus aureus bacterial infection is a health threat. Treatment of infections using antibiotics has been widely used. However, misuse of antibiotics can cause resistance. One way to overcome typically by creating common fixings as antibacterials. BSF larvae oil (MLB) and tuna fish oil (MIT) are known to have antibacterial potential. This study aims to determine the antibacterial activity of the combination of MLB and MIT against S. aureus. The oil characteristics were tested using the titration method and the fatty acid components were analyzed. The antibacterial activity of MLB and MIT was carried out by determining the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values respectively using the microdilution method and observing bacterial growth. The antibacterial activity of the combination was carried out by determining the Fractional Inhibitory Concentration Index (FICI) value. The research results showed that MLB and MIT met the test standards for free fatty acids, saponification value, peroxide value, and iodine value except acid value. The highest fatty acid in MLB and MIT respectively are lauric acid (39.442%) and oleic acid (20.83%). MLB MIC value at a concentration of 6.25% with an inhibition zone of 12.17 mm ± 1.027; and the MIC value of MIT at a concentration of 0.781% with an inhibition zone of 4.83 mm ± 1.247. The MBC results from MLB and MIT stated that the concentration was more than 25%. MIC value for combination of MLB is 6.25% and MIT is 0.781% with an inhibition zone diameter of 7.00 mm ± 2.273. The FICI value for the combination of MLB and MIT against S. aureus bacteria is 2, which shows indifferent characteristics.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2407002112	T142377	T1423772024	Central Library (References)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1423772024

Publisher

Inderalaya : Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2024

Collation

xvii, 137 hlm.; ilus.; tab.; 29 cm.

Language

Indonesia

ISBN/ISSN

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Classification

547.707

Content Type

Text

Media Type

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Carrier Type

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Edition

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Subject(s)

Prodi Ilmu Farmasi
Senyawa Antibakteri Minyak Larva Ikan

Specific Detail Info

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Statement of Responsibility

MI

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