Skripsi
UJI EFEK TERAPEUTIK EKSTRAK DAUN MORINGA OLEIFERA TERHADAP KADAR KOLESTEROL TOTAL DAN GAMBARAN HISTOLOGI HEPAR PADA MENCIT MODEL OBESITAS
This research constitutes an experimental analytic study conducted in vivo, employing two parameters. The investigation of total cholesterol levels was conducted using a pre-test and post-test design with a control group. Conversely, the study of hepatic histology utilized a post-test with a control group design. Thirty male mice were allocated into five groups: a negative control, an obesity control with simvastatin, and obesity groups treated with varying doses of Moringa oleifera leaf extract (420, 630, and 840 mg/kg body weight). Prior to the treatment phase, each group was induced to develop obesity through a high-fat diet, marked by a Lee index>0.3, over a period of eight weeks. Subsequently, the animals were administered interventions daily according to their group allocations for a duration of 14 days. Total cholesterol levels were quantified pre- and post-treatment using Cholesterol (autocheck & GCU) and cholesterol strips, followed by the preparation of hepatic histological specimens for analysis of histological alterations.
Inventory Code | Barcode | Call Number | Location | Status |
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2407000380 | T137634 | T1376342023 | Central Library (Referens) | Available but not for loan - Not for Loan |
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