Skripsi

PERBEDAAN INFILTRASI SEL NEUTROFIL BERDASARKAN KARAKTERISTIK KLINIKOHISTOPATOLOGI JARINGAN KARSINOMA OVARIUM TIPE SEROSA DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

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Penilaian

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Introduction: Ovarian cancer is the main cause of death globally and ranks third as the most common incidence in Indonesian women. Neutrophil cell infiltration in cancer tissue as one of the immune cells that has an important role in the formation of the body's response against cancer but associated with poor prognosis. Neutrophil density is related to the clinicohistopathologic characteristics of ovarian cancer patients. The purpose of this study was to determine the relationship of clinicohistopathologic characteristics with neutrophil cell infiltration of serous type ovarian carcinoma tissue. Methods: This study used a cross-sectional method. The samples used were serous type ovarian carcinoma tissue preparations that had been stained with Hethoxylin-Eosin and clinical data from the Medical Record Installation. Observations were made by identifying neutrophil cells through their morphology that infiltrate the microtumor environment of stromal and intratumoral areas. Results: There were 35 patients diagnosed with serous type ovarian carcinoma. The majority of samples were aged 40-60 years (48.6%) with the most histologic subtype HGSC (74.3%). The majority of the samples were advanced stage (77.1%) with organ metastasis around the pelvis (62.9%). There was no significant difference between neutrophil cell infiltration based on clinicohistopathological characteristics, including age (stromal p=0.845 and intratumoral p=0.223), grading (stromal p=0.299 and intratumoral p=0.720), FIGO stage (stromal p=0.345 and intratumoral p=0.377), and metastasis (stromal p=0.835 and intratumoral p=0.936). Conclusion: There is no significant difference between neutrophil cell infiltration according to location and clinicohistopathological characteristics of serous type ovarian carcinoma tissue at RSUP Dr. Mohammad Hoesin Palembang.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2407000118	T137187	T1371872023	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1371872023

Publisher

Inderalaya : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2023

Collation

xviii, 73 hlm.; Ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

612.107

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

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Subject(s)

Prodi Pendidikan Dokter
Darah dan Peredaran, Sirkulasi Darah

Specific Detail Info

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Statement of Responsibility

SEPTA

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