Skripsi
DISTRIBUSI BAKTERI DAN POLA KEPEKAAN ANTIBIOTIK ISOLAT BAKTERIURIA PADA ANAK DENGAN KEGANASAN DISERTAI DEMAM NEUTROPENIA DI RSUP DR. MOHAMMAD HOESIN PALEMBANG
Background: Urinary tract infection (UTI) is one of the etiologies of febrile neutropenia (FN) in pediatric malignancy, an oncology emergency. Empirical antibiotic prescribing according to guidelines, based on local bacterial and resistance patterns, should be initiated immediately. This study aims to determine the prevalence of UTI, the distribution of bacterial and antibiotic sensitivity patterns of bacteriuria isolates in FN. Methods: This was a descriptive observational study with a cross-sectional design. The study was undertaken at Dr. Mohammad Hoesin Hospital Palembang retrospectively, using data on results of urine culture and antibiotic sensitivity tests in children with febrile neutropenia and malignancies from January 2020 to December 2022. Results: Urine culture was performed in 158 out of 458 episodes of FN in children with malignancy, with a proportion of UTI (33.5%). Most UTIs in FN occurred in early adolescence (12-18 tahun) (41.5%), females (54.7%), and hematologic malignancies (75.5%) dominated by acute lymphoblastic leukemia (51%). The bacteria causing UTIs were mostly Gram-negative (79.3%), with Escherichia coli being the dominant bacterial species (28.9%), Acinetobacter baumannii (13.6%), Enterococcus faecalis (11.9%) and Klebsiella pneumoniae (8.5%). Cephalosporin class antibiotic sensitivities for Eschericia coli and other Gram-negative isolates were
Inventory Code | Barcode | Call Number | Location | Status |
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2407000759 | T137948 | T1379482023 | Central Library (Referens) | Available but not for loan - Not for Loan |
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