Skripsi

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia Pellucida L) TERHADAP Staphylococcus aureus SECARA IN VITRO

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Penilaian

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Introduction: Staphylococcus aureus is one of the opportunistic bacteria in the oral cavity that can cause various diseases, including periapical abscesses. The treatment of microbial infections needed to pay attention to selected antibiotics. Traditional medicine was very popular with the community because it had very minimal side effects and the availability that is easy to obtain. Suruhan leaves could be utilized as an antibacterial due to their content of tannins, saponins, flavonoids and alkaloids which inhibit bacterial growth. Purpose: This study aimed to determine the effectiveness of the antibacterial extract of suruhan leaves (Peperomia pellucida L) against Staphylococcus aureus. Methods: This study was an in vitro laboratory experimental study. The test group used an extract of suruhan leaf with concentrations of 20%, 40% and 60% obtained by the soxhlation method, clindamycin was used as a positive control and aquades as a negative control. The antibacterial potency was tested using the disc diffusion method to determine the value of the inhibition zone, the dilution method to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). The inhibition zone values were then analyzed statistically using one-way ANOVA and Post-Hoc Tukey tests. Results: This study revealed that the 60% concentration of extract suruhan leaf had an average inhibition zone of 18.27 mm, but smaller than clindamycin. The MIC test results of extract suruhan leaf were determined at a concentration of 20% and MBC at 40%. Conclusion: Suruhan leaf extract (Peperomia pellucida L.) had antibacterial activity against Staphylococcus aureus. Keywords: antibacterial, suruhan leaves, Peperomia Pellucida L, Staphylococcus aureus

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2307006111	T105991	T1059912023	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1059912023

Publisher

Inderalaya : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya., 2023

Collation

x, 58 hlm.; Ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

617.601 07

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

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Subject(s)

Kesehatan mulut dan pencegahan sakit gigi
Prodi Kedokteran Gigi dan Mulut

Specific Detail Info

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Statement of Responsibility

SEPTA

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