Skripsi

FORMULASI DAN UJI AKTIVITAS ANTIERITEMA KRIM TABIR SURYA EKSTRAK ETIL ASETAT DAUN SUKUN (Artocarpus altilis (Park.) Fosberg) DENGAN PEMBAWA ASAM STEARAT DAN TRIETANOLAMIN

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Penilaian

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Exposure to direct sunlight for a long time can cause damage to the epidermal tissue of the skin which is a factor in the emergence of erythema and causes skin cancer. Sunscreen is a cosmetic product that functions to protect the skin from exposure to UV rays. Breadfruit leaves (Artocarpus altilis) are reported to contain antioxidant compounds which have the potential to be active ingredients for sunscreen. This study aims to determine the effect of extract concentration on the SPF value and activity of sunscreen cream with active ingredient ethyl acetate extract of breadfruit leaves with variathy concentration. Physical evaluation of cream preparations was carried out by organoleptic test parameters, homogeneity, measurement of pH, viscosity, spreadability, adhesion, washability, stability testing using the centrifugation method and cycling test testing for 6 cycles. The three cream formulations showed physical stability and storage. Measurement of the SPF value of the extract and cream using a UV-Vis spectrophotometer instrument with a wavelength of 290-320nm obtained results with extract values, F1, F2 and F3 respectively; 7,260, 9,906, 11,808, and 14,486. Extracts, F1, F2 and F3 are included in the SPF category with low protection. In vivo testing, the rats were divided into 5 groups as F0 was given no treatment, F1 was given 2% cream extract, F2 was given 4% cream extract, F3 was given 6% cream extract, and F+ was given commercial sunscreen. The results of the activity test showed that group F0 experienced degree 4 erythema while groups F1, F2, F3, and F+ did not experience erythema (degree 0) where it can be concluded that ethyl acetate extract of breadfruit leaves can prevent erythema and edema due to UV exposure and be used as a sunscreen. Keywords: Sunscreen, Cream, Artocarpus altilis extract, UV, Flavonoids, SPF, Erythema Edema

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2307006652	T131777	T1317772023	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1317772023

Publisher

Inderalaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2023

Collation

xvii, 93 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.307

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

-

Subject(s)

Jurusan Farmasi
Obat-obatan organik

Specific Detail Info

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Statement of Responsibility

SEPTA

Other version/related

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