Skripsi

OPTIMASI EKSTRAKSI DAUN GAMBIR (UNCARIA GAMBIR ROXB.) MENGGUNAKAN METODE ULTRASOUND ASSISED EXTRACTION DAN AKTIVITASNYA SEBAGAI ANTIOKSIDAN

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Penilaian

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Catechins compounds in gambier leaves have an antioxidant effect. The purpose of this study is to determine the optimal results of gambir leaf extract and the characteristic of optimal gambier leaf extract. The extraction method used in the study was ultrasoundassisted extraction (UAE). Data analysis was carried out using software design expert 13 with factorial 23. Factors in the extraction process used are times (10-30 minutes), temperature (20-500C), and material: solvent ratio (1:7-1:10). The response of the observed study results consisted of % extract yield, total flavonoid contents (TFC), and antioxidant activity (IC50) of the extract. The optimal process factor condition results are selected based on the condition with the highest desirability value. The optimal results of gambier leaf extract based on the extraction process factor were obtained in the extraction treatment time 30 minutes, temperature 500C, with a ratio of material: solvent 1:10 which % yield extract 7,8%; total flavonoid contents 467,514 mgCE/g; and antioxidant activity value of 66,013 ppm with a desirability value 0,998. The characteristics of the optimal gambier leaf extract have a moisture content 0,13% and a drying shrinkage 0,15%. The phytochemical screening results of optimum gambier leaf extract wer found positif for phenolic, flavonoids, and tannins. The results of verification optimal condition of extract obtained are in the range of 95% PI low and 95%PI high which indicates that there is a conformity to the predicted value with the value of observations that have been made.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2307003781	T126230	T1262302023	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T1262302023

Publisher

Inderalaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2023

Collation

xvii, 108 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.307

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

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Subject(s)

Jurusan Farmasi
Obat-obatan organik

Specific Detail Info

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Statement of Responsibility

SEPTA

Other version/related

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