Skripsi
UJI TOKSISITAS SUBKRONIS FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR
Purple sweet potato leaves (Ipomoea batatas L.) is a traditional medicine so it is necessary to carry out safety tests, one of which is the subchronic toxicity test. This study aims to determine the effect subchronic toxicity of the ethyl acetate fraction of purple sweet potato leaves on male white rats of the Wistar strain. In this study, they were divided into 4 groups including the control group Na-CMC 0.5% and the ethyl acetate fraction of purple sweet potato leaves (110.5 mg/kgBW, 221 mg/kgBW and 442 mg/kgBW). Administration of preparations was carried out for 28 days and 14 days of observation of delayed effects. Parameters observed included body weight, blood hematology, blood biochemistry, macroscopic and histopathology of the liver and kidneys. The results showed that the change in body weight of the treated rats for 28 days and 42 days was not significantly different for each group (p>0.05). There was no significant difference in the blood biochemical and hematological parameters after administration of the test preparation for 28 days (p>0.05) but there was a significant difference in the SGPT levels of the rats (p
Inventory Code | Barcode | Call Number | Location | Status |
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2307004553 | T126345 | T1263452023 | Central Library (Referens) | Available but not for loan - Not for Loan |
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