Skripsi

UJI AKTIVITAS ANTIHIPERLIPIDEMIA FRAKSI N-HEKSANA DAUN UBI JALAR UNGU ( Ipomoea batatas (L.) Lam.) TERHADAP TIKUS PUTIH JANTAN YANG DIINDUKSI SUPLEMEN TINGGI LEMAK

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Penilaian

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Purple sweet potato (Ipomoea batatas (L.) Lam.) leaf contain beta carotene compounds which have antihyperlipidemia activity. This study aims to determine the antihyperlipidemia effect of n-hexane fraction of purple sweet potato leaves on total cholesterol, triglyceride, HDL and LDL levels in rat serum induced by PTU and high fat supplements. This study divided into 6 groups, normal group, positive group (Fenofibrate dose 19,76 mg/kgBB) , negative group (0.5% NaCMC), group 1 (50 mg/kgBB), group 2 (100 mg/kgBB), and group 3 (200 mg/kgBB). Parameters measured in the form of total cholesterol levels, triglycerides, LDL and HDL were carried out by an enzymatic colorimetric method using the glycerol phospate oxidase p-aminophenazone (GPO-PAP) reagent for triglycerides, cholesterol oxidase p-aminoantipyrine (CHOD-PAP) reagents for total cholesterol, precipitation methods for HDL, indirect for LDL. Based on the results of the research that has been done show that the %PKKT in groups 1, 2 and 3 amounted to 22.2%, 43.3% and 52.8%. Group 3 with dose of 200 mg/kgBB had the best antihyperlipidemia activity among the 3 treatment groups with a decrease in total cholesterol levels of 52.8%. The analysis results obtained showed a decrease in lipid levels and there was a significant difference compared to the negative group (p

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2307000365	T89100	T891002023	Central Library (Referens)	Available

Detail Information

Series Title

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Call Number

T891002023

Publisher

Indralaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2022

Collation

xix, 121 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.307

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Jurusan Farmasi
Obat yang berasal dari Tumbuhan

Specific Detail Info

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Statement of Responsibility

PITRIA

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