Skripsi

PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.) TERHADAP SEL IMUN TIKUS PUTIH GALUR WISTAR

---

Penilaian

---

Kenikir leaves (Cosmos caudatus. Kunth) contain various secondary metabolic compounds, quercetin which has the potential as an immunomodulator. This study aims to determine number of leukocytes, lymphocytes, neutrophils, monocytes, CD4 T cells, ODF ethanol extract film of kenikir leaves in Wistar rat strain and macroscopic and histopathalogic images of spleen organs. The research used Spektrofotometri UV-Vis, Hematalogy Analyzer and Pima Analyzer, Hematoxylin Eosin (HE) staining on spleen preparations and male white rats wistar strain weighing 150-250 grams and aged 2-3 months which were divided into 5 groups were divided into five groups. Normal (food), positive control (Stimuno), negative control (Orally Disollvong Film), Group I (Kenikir Leaves Extract), and group II (Orally Dissolving Film of Kenikir Leaves Extract). The total flavonoid content was 485.26 mg/gram of extract. Orally Dissolving Film Kenikir leaf extract has a film thickness of 0.09 mm, folding durability of 300, crushing time of 27.42 seconds, pH 4.05, weight uniformity of 2.313 ± 0.006 mg, uniformity of levels with 99.998% ± 0.337 and percent elongation up to 22.973%. Giving of Orally Dissolving Film extract ethanol of kenikir leaves dose 35 mg / kg BB treated group showed a significant (p

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2307002487	T114046	T1140462023	Central Library (Referens)	Available

Detail Information

Series Title

-

Call Number

T1140462023

Publisher

Indralaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2023

Collation

xviii, 146 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

-

Classification

615.307

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Jurusan Farmasi
Obat-obatan organik

Specific Detail Info

-

Statement of Responsibility

PITRIA

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment