Image of EFEK PEMBERIAN SELF-NANO EMULSION EKSTRAK WHITE TEA TERHADAP PROFIL INSULIN, PARAMETER STRES OKSIDATIF DAN MIKROANATOMI TESTIS PADA MODEL TIKUS DIABETES TIPE-2

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EFEK PEMBERIAN SELF-NANO EMULSION EKSTRAK WHITE TEA TERHADAP PROFIL INSULIN, PARAMETER STRES OKSIDATIF DAN MIKROANATOMI TESTIS PADA MODEL TIKUS DIABETES TIPE-2

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White tea contains catechins which have pharmacological effects as antioxidants. This study used test animals in the form of male Wistar rats which were divided into seven groups: normal group, negative control (STZ-NA induced), positive control (STZ-NA and Glibenclamide induced), group 1 (STZ-NA induced and SNE base). , Group 2 (induced STZ-NA and SNE-white tea extract), group 3 (induced STZ-NA and white tea extract), and group 4 (induced STZ-NA and catechins). The purpose of this study was to determine the effectiveness of SNE-Extra white tea in treating type-2 diabetes, repairing oxidative stress, and testicular microanatomy. The parameters observed in this study were the insulin profile which included insulin levels in the body, the level of insulin resistance in the form of a homeostatic model assessment of insulin resistance (HOMA-IR), the level of damage to pancreatic beta cells in the form of a Homeostatic Model Assessment of Beta Cell Function (HOMA-ß). , parameters of oxidative stress including GSH and GPx, as well as testicular microanatomy parameters using Johnson's assessment, degree of necrosis, and level of fatty degeneration. This study shows that SNE-white tea extract is effective in increasing insulin levels, reducing insulin resistance, repairing pancreatic beta cells, improving oxidative stress, and improving testicular microanatomy.

Availability
Inventory Code Barcode Call Number Location Status
2307000789T88930T889302023Central Library (Referens)Available
Detail Information
Series Title
-
Call Number
T889302023
Publisher
Indralaya : Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya.,
Collation
xvii, 125 hlm.; ilus.; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
615.307
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Jurusan Farmasi
Obat-obatan organik
Specific Detail Info
-
Statement of Responsibility
Other version/related

No other version available

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