Skripsi

ISOLASI SENYAWA TURUNAN POLIKETIDA DARI FRAKSI ETIL ASETAT BATANG TUMBUHAN TITHONIA DIVERSIFOLIA

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Penilaian

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Tithonia diversifolia is a plant from the Asteraceae family of the genus Tithonia, originating from North and Central America. T. diversifolia has been reported as a biofumigant, anti-TMV (Tobacco mosaic virus), insecticide, antidiabetic, and antioxidant both from extracts, fractions, and metabolites that were successfully isolated. The content of secondary metabolites from T. diversifolia leaves and aerial parts was reported more than the stem. Based on this knowledge, the research will be carried out to isolate and identify the secondary metabolites present in the stem of this plant. The extraction process was carried out by the maceration method, using methanol as a solvent. Then proceed with the liquids fractionation process using n-hexane solvent followed by ethyl acetate solvent. The process of isolation or separation and purification of compounds was carried out using VLC (vacum liquid chromatography) and GCC (gravity chromatography column). The isolated compound obtained as a white crystals (38.8 mg) and has a melting point of 147.3℃-148.9℃. Structural characterization of the isolated compound was concluded using UV-Vis spectroscopy, IR, and NMR spectroscopy (1H-NMR, 13C-NMR, HSQC, and HMBC). Based on the spectroscopic data and comparison with literature data, concluded that the isolated compound was a polyketide derivative, namely De-O-methylacetovanillochromene.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2307002898	T120622	T1206222023	Central Library (Referens)	Available

Detail Information

Series Title

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Call Number

T1206222023

Publisher

Indralaya : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2023

Collation

xx, 56 hlm.; ilus.; 21 cm

Language

Indonesia

ISBN/ISSN

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Classification

547.707

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Jurusan Kimia
Senyawa Turunan

Specific Detail Info

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Statement of Responsibility

PITRIA

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