Skripsi

PENGARUH GELATIN KULIT IKAN PATIN (PANGASIUS SP) TERHADAP PENINGKATAN JUMLAH SEL MAKROFAG DAN FIBROBLAS ULKUS TRAUMATIKUS.

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Penilaian

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Background: Traumatic ulcer are lesions of the oral mucosa caused by thermal, mechanical and chemical. Long-term use of topical medication can lead resistance to fungal infection. Several studies have shown that patin fish skin contains glycine and glutamic acid which can increase macrophage activation and fibroblast proliferation in the wound healing process that wound healing will be accelerated. Aim : to determined the effect of gelatin skin catfish to increasing macrophage and fibroblast and decreasing the diameter of traumatic ulcer. Method: A true experimental laboratories with postest only control group design. 24 wistar strain male rats were devided into 4 groups. Ulcer was made on the labial mucosa of mandibular by thermal induction. Ulcer was tread with placebo gel and gelatin skin catfish with 10%, 20% and 30% concentration for 7 days. Rats were euthanazied on days 3,5,7 and ulcerated mucosal tissue was biopsied to count the number of macrophage and fibroblast using olympus software. Data were analyzed using IBM SPSS statistic 25 version. Result: Gelatin skin catfish with 10%, 20% and 30% concentration had a difference in mean from the 3rd, 5th and 7th days. Based on Npar test there were significant differences in number of macrophages cells between the gelatin skin catfish treatment groups with 10%, 20% and 30% concentration. Based on post hoc test there was significant difference in the number of fibroblast cell gelatin skin catfish with 10%, 20% and 30% concentration compared to placebo gel (p

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2207004190	T80126	T801262022	Central Library (Referens)	Available

Detail Information

Series Title

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Call Number

T801262022

Publisher

Indralaya : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya., 2022

Collation

xviii, 55 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

619,907

Content Type

Text

Media Type

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Carrier Type

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Edition

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Subject(s)

Prodi Kedokteran Gigi dan Mulut
Kedokteran Eksperimental pada Mamalia dan Manusia

Specific Detail Info

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Statement of Responsibility

MURZ

Other version/related

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