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UJI AKTIVITAS DIURETIK FRAKSI ETIL ASETAT DAUN NANGKA (Artocarpus heterophyllus) PADA TIKUS PUTIH JANTAN WISTAR
Diuretics are used as drugs to treat hypertension. Diuretics work to remove excess fluid in the body by increasing the process of urine formation. The secondary metabolite content in jackfruit leaves which is thought to have potential as a diuretic is phenolic compounds. This study aims to determine the diuretic activity of the ethyl acetate fraction of jackfruit leaves. Total phenolic content was determined by colorimetric method. Diuretic activity testing was carried out on 6 groups of test animals including normal, negative, positive groups, and three groups of test doses of ethyl acetate fraction 25, 50 and 100mg/200gBW. The total phenolic content of the ethyl acetate fraction of jackfruit leaves was 51 mg GAE/g. The results showed that the 100 mg/200gBW dose group could increase the excretion of urine volume and the Na+, K+ and Clions were higher than the positive group (p
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2207001662 | T71219 | T712192022 | Central Library (Referens) | Available but not for loan - Not for Loan |
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