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SKRINING METABOLIT SEKUNDER DAN UJI TOKSISITAS PADA ESTRAK RUMPUT LAUT Glacilaria sp. dan Gelidium sp. DARI PERAIRAN KALIANDA, LAMPUNG SELATAN

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Penilaian

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Seaweed is one of the natural ingredients that have a variety of contents and sources of secondary metabolite compounds that have toxic activity. Toxic activity derived from a substance can be further developed and will provide benefits in the field of food and pharmacology. The presence of seaweed Glacilaria sp. and Gelidium sp. in the coastal area of Kalianda waters, South Lampung is quite abundant so that due to the availability of the abundance of these materials can be made of great potential to be utilized as a medicine. The purpose of this study was to analyze the level of toxicity using stratified estraction with n-hexane and methanol solvents and analyze chemical components with GC-MS based on the highest level of toxicity. The study was conducted from November to December 2021. Samples of Glacilaria sp. and Gelidium sp. taken from the waters of Kalianda, South Lampung. Furthermore, the samples were tested for toxicity by Brine Shrimp Lethality Test, phytochemical analysis, and GC-MS analysis. Based on the toxicity test results, the value of lc50 estrak n-hexane Glacilaria sp. 8446 µg/mL, methanol Glacilaria sp. 694 µg/mL n-hexane Gelidium sp. µg/mL and methanol gelidium sp. it amounted to 339 µg/mL. Phytochemical test results contain alkaloids, flavonoids, steroids and saponins while GC-MS test results contain steroids, flavonoids and diterpenoids. Differences in the level of toxicity of n-hexane and methanol in sebabakan by the nature of the compound so that the toxicity of methanol estrak Gelidium sp. higher. Differences in phytochemical test results and GC-MS are based on the percentage level of the compound in the material, so it is likely that compounds with a small percentage will not be detected in the phytochemical test.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2207001298	T71042	T710422022	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T710422022

Publisher

Inderalaya : Jurusan Ilmu Kelautan, Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2022

Collation

xx, 65 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

572.407

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Jurusan Ilmu Kelautan
Metabolisme

Specific Detail Info

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Statement of Responsibility

SEPTA

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