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Image of IDENTIFIKASI SENYAWA ALKALOID BUAH TEMBESU (FAGRAEA FRAGRANS ROXB) DAN UJI AKTIVITAS ANTIBAKTERI

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IDENTIFIKASI SENYAWA ALKALOID BUAH TEMBESU (FAGRAEA FRAGRANS ROXB) DAN UJI AKTIVITAS ANTIBAKTERI

Maizur, Dian Dwita - Personal Name;

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Tembesu (Fagraea fragrans Roxb) are widely grown in the Ogan Ilir area, South Sumatra. Tembesu fruit is a plant that contains alkaloid compounds and has many benefits as herbal medicine. This research aims to identify the alkaloid compounds contained in the tembesu fruit and the antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa bacteria. Alkaloids are known as organic base compounds containing nitrogen atoms but the degree of basicity varies. The alkaloid compounds in this study were extracted using the maceration method using ether as a solvent and liquid-liquid extraction using ethyl acetate as a solvent. The purification process was carried out by gravity column chromatography (KKG) and eluted with 40% ethyl acetate in n-hexane. Three alkaloid compounds have been identified from tembesu fruit based on the LCMS data obtained. The three compounds are genentialutine, gentianine, and isaindigotone. The LCMS spectral results gave protonated molecular ion peaks at m/z (r.t. min) = 150.08 (1.39), 176.06 (4.53), and 351.37 (5.23) respectively. The antibacterial activity test data showed that the alkaloid compounds from the tembesu fruit did not provide a value for the diameter of the inhibition zone against S. aureus and P. aerginosa bacteria, so it can be seen that the isolated alkaloid compounds from tembesu fruit did not have antibacterial properties.


Availability
Inventory Code Barcode Call Number Location Status
2207000477T65562T655622022Central Library (Referens)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T655622022
Publisher
Inderalaya : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2022
Collation
xx, 36 hlm.; ilus.; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
546.380 7
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Jurusan Kimia
Logam Alkali dan Alkaline, Grup 1A
Specific Detail Info
-
Statement of Responsibility
SEPTA
Other version/related

No other version available

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  • IDENTIFIKASI SENYAWA ALKALOID BUAH TEMBESU (FAGRAEA FRAGRANS ROXB) DAN UJI AKTIVITAS ANTIBAKTERI
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