Skripsi

EFEK ANTIJAMUR EKSTRAK ETIL ASETAT DAN EKSTRAK METANOL DAUN KAMBOJA MERAH (Plumeria rubra L.) TERHADAP Candida albicans SECARA in vitro

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Penilaian

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Background: This research was conducted to know whether Plumeria rubra leaves extract has antifungal activity against Candida albicans causing candidiasis; to know wich extract has better effect against Candida albicans growth; and to assess The Minimum lnhibitory Concentration (MIC). Methods: This research was designed as laboratory experimental, using Posttest Only Control group design. Plumeria leaves extract was obtained by multilevel maceration method using two solvents, consist aethyl acetat, and methanol. Then, extract was tested to perform antifungal activity against Candida albicans using Kirby-Bauer Disc Method and then the result was statistically analyzed by SPSS version 18 for Windows. Results: Both of Plumeria rubra leaves extract from aethylacetat and methanol solvents can inhibit the Candida albicans growth in the Sabouroud Dextrose Agar medium. And both of them have the same effectiveness in term of antifungal activity in inhibiting the Candida albicans growth. The minimum inhibitory concentration (MIC) for aetil acetat extract is 0,02 gr/ml; and for methanol extract is 0,03 gr/ml. The concentration of aetyl acetat extract has an average level of correlation to the inhibitory zone diameter according to its Pearson correlation value (r = 0,394); but this correlation is not significant based on its significant value (p = 0,131) while the concentration of methanol extract has a strong level of correlation to the inhibitory zone diameter with its Pearson correlation value (r) 0,744 and significant value (p) — 0,000. Conclusion: Both of Plumeria rubra leaves extract from aethyl acetat and methanol solvents has antifungal activity in inhibiting Candida albicans growth in Sabouroud Dextrose Agar media.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
1207000238	T87680	T876802012	Central Library (REFERENCES)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T876802012

Publisher

Inderalaya : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2012

Collation

xii, 78 hlm.; ill.; tab.; 28 cm.

Language

Indonesia

ISBN/ISSN

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Classification

616.969

Content Type

Text

Media Type

unmediated

Carrier Type

unspecified

Edition

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Subject(s)

Antijamur
Prodi Pendidikan Dokter

Specific Detail Info

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Statement of Responsibility

Furika

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