The Sriwijaya University Library

  • Home
  • Information
  • News
  • Help
  • Librarian
  • Login
  • Member Area
  • Select Language :
    Arabic Bengali Brazilian Portuguese English Espanol German Indonesian Japanese Malay Persian Russian Thai Turkish Urdu

Search by :

ALL Author Subject ISBN/ISSN Advanced Search

Last search:

{{tmpObj[k].text}}
Image of ANALISIS SECARA IN-VITRO AKTIVITAS ANTI-HIPERKOLESTEROLEMIA SENYAWA POLIFENOL DAN FLAVONOID DAUN TUMBUHAN APU-APU (Pistia stratiotes)

Text

ANALISIS SECARA IN-VITRO AKTIVITAS ANTI-HIPERKOLESTEROLEMIA SENYAWA POLIFENOL DAN FLAVONOID DAUN TUMBUHAN APU-APU (Pistia stratiotes)

Janna, Miftahul - Personal Name;

Penilaian

0,0

dari 5
Penilaian anda saat ini :  

In-vitro Analysis of Anti-hypercholesterolemia Activity of Polyphenol and Flavonoid Compounds Water Lettuce (Pistia stratiotes) Leaf (supervised by Sabri Sudirman). The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase is an enzyme that plays a role in the synthesis of cholesterol. Synthetic anti-cholesterol drugs such as statins have been used as HMG-CoA reductase inhibitors. However, these drugs have side effects, so natural HMG-CoA reductase inhibitors such as from plants origin are needed. This study aimed to determine the in vitro potential inhibitory HMG-CoA reductase activity as an anti-hypercholesterolemia property of the water lettuce (Pistia stratiotes) leaf extracts. The research was conducted experimentally in a laboratory with a treatment consisting of 2 levels, namely crude extract and purified extract and repeated 3 times. Total polyphenols, flavonoids, and inhibitory activity of the HMG-CoA reductase assay were carried out by in vitro analysis. The results obtained were analyzed quantitatively, followed by using different parametric statistics (Independent sample t-test), and presented in graphical form. The results of this study showed that the yield of the extract was 4.13% (crude extract) and 3.34% (purified extract). The total polyphenols in each extract were 29.03 mg GAE/g dry sample (crude extract) and 65.63 mg GAE/g dry sample (purified extract). The total flavonoids were 27.58 mg QE/g dry sample (crude extract) and 88.02 mg QE/g dry sample (purified extract). The inhibitory activity of the HMG-CoA reductase enzyme showed that the purified extract could inhibit (34.74%) higher than the crude extract (2.61%). The purified extract of water lettuce has higher levels of polyphenols and flavonoids and can inhibits the HMG-CoA reductase enzyme more effectively than crude extract. Keywords: Anti-hypercholesterolemia, HMG-CoA reductase, Pistia stratiotes, polyphenol.


Availability
Inventory Code Barcode Call Number Location Status
2207001689T71434T714342022Central Library (Referens)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T714342022
Publisher
Inderalaya : Prodi Teknologi Hasil Perikanan, Jurusan Perikanan, Fakultas Pertanian., 2022
Collation
xiv, 43 hlm.; ilus.; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
633.207
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Tanaman Pakan Ternak
Prodi Teknologi Hasil Perikanan
Specific Detail Info
-
Statement of Responsibility
SEPTA
Other version/related

No other version available

File Attachment
  • ANALISIS SECARA IN-VITRO AKTIVITAS ANTI-HIPERKOLESTEROLEMIA SENYAWA POLIFENOL DAN FLAVONOID DAUN TUMBUHAN APU-APU (Pistia stratiotes)
Comments

You must be logged in to post a comment

The Sriwijaya University Library
  • Information
  • Services
  • Librarian
  • Member Area

About Us

As a complete Library Management System, SLiMS (Senayan Library Management System) has many features that will help libraries and librarians to do their job easily and quickly. Follow this link to show some features provided by SLiMS.

Search

start it by typing one or more keywords for title, author or subject

Keep SLiMS Alive Want to Contribute?

© 2025 — Senayan Developer Community

Powered by SLiMS
Select the topic you are interested in
  • Computer Science, Information & General Works
  • Philosophy & Psychology
  • Religion
  • Social Sciences
  • Language
  • Pure Science
  • Applied Sciences
  • Art & Recreation
  • Literature
  • History & Geography
Icons made by Freepik from www.flaticon.com
Advanced Search