Skripsi

ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI FRAKSI n-HEKSANA RANTING RUKAM (Flacourtia rukam)

---

Penilaian

---

Rukam plant (Flacourtia rukam) is one of the plants of the genus Flacourtia. Almost all parts of the rukam plant have been used traditionally for the treatment of various diseases, but no information has been found in the use of the branches. The purpose of this study was to isolate and determine the antibacterial activity of secondary metabolites from the n-hexane fraction of rukam twigs. The study began with the extraction of compounds by maceration using n-hexane as a solvent. The separation and purification of compound was carried out by chromatographic techniques. The structure of the compound was determined based on the analysis of spectroscopic data of FT-IR, 1H-NMR, 13C-NMR, and comparative literature. Antibacterial activity was determined by disc diffusion method using Escherichia coli and Staphylococcus aureus as test bacteria and determination of minimum inhibitory concentration (MIC) was carried out by micro dilution method. The isolated pure compound was in the form of white crystals (31 mg). Based on the analysis of spectroscopic data and comparative literature, the isolated compound belongs to the triterpenoid group, namely friedelin. This compound has been previously reported. Pure compound exhibits antibacterial activity against E. coli and S. aureus bacteria with a minimum inhibitory concentration value of 120 g/mL.

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2107004014	T50803	T508032021	Central Library (Reference)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T508032021

Publisher

Inderalaya : Prodi Ilmu Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2021

Collation

xvii, 39 hlm.; tab.; 21 cm.

Language

Indonesia

ISBN/ISSN

-

Classification

669.607

Content Type

Text

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Mipa Kimia
Antibakteri Senyawa Metabolit Sekunder

Specific Detail Info

-

Statement of Responsibility

MI

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment