Skripsi

UJI AKTIVITAS ANTIJAMUR EKSTRAK BUAH MENGKUDU (MORINDA CIRTIFOLIA L.) TERHADAP JAMUR CANDIDA ALBICANS

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Penilaian

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Research on efficacious plants as medicines continue to be developed to treat various diseases. This research aimed to determine the benefits of noni fruit methanol extract in the fractions of chloroform, ethyl acetate, and 2-propanol in inhibiting the growth of the fungus Candida albicans. This research began with extraction method - maceration using methanol solvent which was then continued with multilevel fractionation. The antifungal activity test used the disc diffusion method with test fungus Candida albicans, then the antifugal activity test were continued with the minimum inhibitory concentration test using the turbidimetric method. The results of phytochemical screening in noni fruit in the 2-propanol fraction had the most metabolites in flavonoid and tannin compounds, ethyl acetate fraction in alkaloids and saponins, and chloroform fraction in steroid compounds. The 2-propanol fraction at a concentration of 1.000 ug /mL gave antifungal activity of Candida albicans with an inhibition zone diameter 0f 17.667 mm while ethyl acetate gave an inhibition zone of 10.333 mm and chloroform fraction of 15.667 mm at the same concentration. The results of the turbidimetric test of the minimum inhibitory concentration at 125 ug /mL was the minimum inhibitory concentration of Candida albicans fungus growth. Based on the results of the research, the methanol extract in the 2-propanol fraction of the noni fruit inhibit the fungus Candida albicans more effectively than the ethyl acetate and chloroform fractions.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003981	T57835	T578352021	Faculty of Economics (Reference)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T578352021

Publisher

Inderalaya : Prodi Ilmu Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2021

Collation

xviii, 47 hlm.; tab.; 21 cm.

Language

Indonesia

ISBN/ISSN

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Classification

547.07

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Mipa Kimia
Ektrak Metanol Buah Mengkudu

Specific Detail Info

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Statement of Responsibility

MI

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