Skripsi

UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN CEMPEDAK (ARTOCARPUS CHAMPEDEN) DAN HISTOPATOLOGI HEPAR TERHADAP TIKUS PUTIH JANTAN GALUR WISTAR TERINDUKSI CCl4

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Penilaian

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The leaves of cempedak (Artocarpus champeden) contain secondary metabolites in the form of flavonoid compounds which can be potential hepatoprotectors. This study aims to determine the effect of giving cempedak (Artocarpus champeden) leaf ethanol extract on the histopathological image of the liver of male white rats induced by carbon tetrachloride (CCl4) based on measurement parameters of SGPT and SGOT levels, macroscopic image and histopathology of rat liver organs. The leaves of cempedak (Artocarpus champeden) were extracted using 96% ethanol for 2x24 hours. Testing of hepatoprotector activity was carried out for 16 days using 30 rats which were divided into 6 treatment groups, namely the normal control group (Na CMC 1%), positive (silimarin 200 mg / kgBW), negative (CCl4 1 mL / kgBB), and the ethanol extract test group of cempedak leaves with a dose of 250, 500 and 1000 mg / kgBB. The results showed that the ethanol extract of cempedak leaves could be efficacious as a hepatoprotector with% hepatoprotector effect (% EH) for SGPT and SGOT levels in test group I of 54,16% and 47,92%, test group II of 76,70% and 65,80% and the third test group of 97.66% and 84,19%. The results showed that the ethanol extract of cempedak leaves significantly (p

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003672	T51263	T512632021	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T512632021

Publisher

Indralaya : Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2021

Collation

xix, 85 hlm,: ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.707

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Prodi Farmasi
Farmakokinetik Daun Cempedak

Specific Detail Info

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Statement of Responsibility

MURZ

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