Skripsi

PREPARASI DAN KARAKTERISASI SUBMIKRO PARTIKEL PEMBAWA GETAH BUAH PEPAYA GUNUNG (CARICA PUBESCENS LENNE & K. KOCH) DENGAN VARIASI KONSENTRASI CACL2 MENGGUNAKAN METODE GELASI IONIK

---

Penilaian

---

Research has been carried out on the preparation and submicro characterization of particles carrying the sap of mountain papaya (Carica pubescens Lenne & K. Koch) with various concentrations of CaCl2 using the ionic gelation method. This study aims to determine the effect of variations in the concentration of CaCl2 on the sub-micro particle formula. Exudate of mountain papaya fruit contains several secondary metabolite compounds, namely flavonoids, alkaloids, steroids, and saponins. It is known that the level of flavonoids in the exudate of the mountain papaya fruit is 21.8363 mg / g. Preparation of submikro done by coating exudate particles with a polymer chitosan and sodium alginate and CaCl2 as crosslinker, varying concentrations of CaCl2 at 20, 40 and 100 mL. The three sub-micro particle formulas produced percent values encapsulation efficiency (EE) of 92.57%, 91.46%, and 91.19%, respectively. The results of sub-micro-particle characterization for diameter, PDI, and zeta potential using a particle size analyzer (PSA) at the best formulas were 296.2 nm, 0.494, and +37.4 mV, respectively. The results of the stability test on submicro particle preparations by heating cooling cycle showed no organoleptic changes and significant pH changes from cycle 1 to cycle 6.

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003492	T40337	T403372021	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T403372021

Publisher

Indralaya : Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2021

Collation

xvi, 71 hlm,: ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

-

Classification

615.107

Content Type

Text

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Prodi Ilmu Farmasi
Materi Medika, Analisis Farmasi

Specific Detail Info

-

Statement of Responsibility

MURZ

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment