Skripsi

UJI EFEK TERATOGENIK EKSTRAK ETANOL DAUN MELINJO (Gnetum gnemon L.) PADA FETUS MENCIT (Mus musculus) GALUR SUB SWISS WEBSTER

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Penilaian

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One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The dosage given is 700, 850, 1000 and 1150 mg/kgBW. The extract was administered during the organogenesis days of the 9th to 17th days of pregnancy and then the mother mice were dissected on the 18th day to observe the fetus weight, live fetus, dead fetus, implantation, resorption, fetus external abnormalities and fetus skeletal disorders. The result of statistic analysis with ANOVA and Kruskall-Wallis followed by DMRT AND Mann-Whitney showed that extract have a significant effect on pregnant mice weight gain, fetus weight, delay of supraoccipital bone, sacrocaudal vertebra body, sternum bone (shaped), sternum bone (dumbbell-shaped), anterior intermediate phalanx and posterior proximal phalanx (p

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003483	T51833	T518332021	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T518332021

Publisher

Indralaya : Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam., 2021

Collation

x, 71 hlm,: ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.707

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Prodi Ilmu Farmasi
Farmakodinamik-Ekstrak Etanol Daun Melinjo

Specific Detail Info

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Statement of Responsibility

MURZ

Other version/related

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