Skripsi

UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN KOPI ROBUSTA (Coffea canephora) TERHADAP TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ALOKSAN

---

Penilaian

---

Antidiabetic activity test of ethanolic extract coffee robusta‟s leaves (Coffea canephora) to rats induced by alloxan has been done. Male wistar albino rats are used as animal models which divided into 6 groups, normal group (aquadest), negative control group (Na CMC 0,5%), positive control group (glibenclamide 0,43 mg/200 gBB), and 3 test group (ethanolic extract of coffee robusta‟s leave 53,5, 107, dan 214 mg/kgBB). Rats blood glucose level after induced intraperitoneally by alloxan 130 mg/kgBB can be stated as diabetic when >200 mg/dL. Preprandial blood glucose levels are measured using DTN-410-K photometer, on day 0, 5, 10, and 15. The result of AUC0-15 and percentage of decreasing blood sugar levels for positive control group are 2747,52 and 37,95%, and 3 treatment groups (53,5 mg/kgBB, 107 mg/kgBB, and 214 mg/kgBB) 3598,32 and 17,59%; 3275,80 and 25,00%; 2770,05 and 36,53%. This point indicated that the ethanolic extract of coffee robusta‟s leaves has an antidiabetic activity and there is no significant difference compared with glibenclamide (p

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
1707000410	T17663	T176632017	Central Library (REFERENCES)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T176632017

Publisher

Inderalaya : Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2017

Collation

xvii, 61 hlm.; ill.; tab.; 28 cm.

Language

Indonesia

ISBN/ISSN

-

Classification

619.907

Content Type

Text

Media Type

unmediated

Carrier Type

unspecified

Edition

-

Subject(s)

Prodi Farmasi
Kedokteran Eksperimental pada Mamalia dan Manusia

Specific Detail Info

-

Statement of Responsibility

Furika

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment