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UJI EFEKTIVITAS ANTIULSER EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ETANOL

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Jackfruit leaves (Artocarpus heterophyllus Lam.) contain secondary metabolites such as flavonoids which have antioxidant and anti-inflammatory activities. This study aims to determine the anti-ulcer effectiveness of jackfruit leaves ethanol extract against white male wistar rats induced by absolute ethanol. The extract was obtained by maceration method using ethanol 96%. The animals were devided into 6 groups. The normal group was given 0.5% of Na CMC, the positive group was given omeprazole 20 mg/kgBW in 0.5% Na CMC, the negative group was only given 0.5% Na CMC, group 1 was given 100 mg/kgBW of ethanol extract of jackfruit leaves, group 2 was given 200 mg/kgBW of ethanol extract of jackfruit leaves, and group 3 was given 400 mg/kgBW of ethanol extract of jackfruit leaves for 14 days. All treatment groups were induced by ethanol absolute on day 15 except the normal group. The total flavonoid content contained in jackfruit leaf extract was 42.571 mgQE/g extract with a percentage of 4.257%. The test results showed that the ethanol extract of jackfruit leaves (200 and 400 mg/kgBW) was able to prevent gastric damage where there was a significant difference compared to the negative control (p

Availability
Inventory Code Barcode Call Number Location Status
2107003682T58824T588242021Central Library (REFERENCES)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T588242021
Publisher
Inderalaya : Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya.,
Collation
xvi, 87 hlm. : ilus. ; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
615.707
Content Type
Text
Media Type
unmediated
Carrier Type
unspecified
Edition
-
Subject(s)
Prodi Farmasi
Farmakodinamik
Specific Detail Info
-
Statement of Responsibility
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No other version available

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