Image of UJI EFEK GASTROPROTEKTIF EKSTRAK ETANOL AKAR TUNJUK LANGIT (HELMINTHOSTACHYS ZEYLANICA L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR DIINDUKSI ETANOL

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UJI EFEK GASTROPROTEKTIF EKSTRAK ETANOL AKAR TUNJUK LANGIT (HELMINTHOSTACHYS ZEYLANICA L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR DIINDUKSI ETANOL

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Tunjuk langit rhizome (Helminthostachys zeylanica L.) had active compounds such as flavonoids as antioxidant and anti-inflammatory. Peptic ulcer are lesions of an inflammatory on the gastric mucosa caused by an imbalance between aggressive and defensive factors. The purpose of this study in order to determine the effect of gatroprotective in tunjuk langit rhizome extract on white male Wistar rats induced by absolute ethanol. The extract was obtained by maceration using ethanol solvent 96%. The animal testing were divided into 6 groups, with normal control group using 0.5% Na-CMC, positive control using 20mg/kgBB of omeprazole in 0.5% Na-CMC, negative control using 0.5% Na-CMC, and the treatment group I using extract of tunjuk langit rhizome 100 mg/kgBB, treatment II using extract of tunjuk langit rhizome 200 mg/kg BB, and treatment III using extract of tunjuk langit rhizome 400 mg/kgBB for 14 days. The results of total flavonoid test showed that tunjuk langit rhizome contained 5,11% flavonoids. The ethanol extract of tunjuk langit rhizome was able to protect the gastric mucosal damage of rats where the dose group (100, 200 and 400) mg/kgBB showed a significant difference compared to negative control (p

Availability
Inventory Code Barcode Call Number Location Status
2107003686T51037T510372021Central Library (REFERENCES)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T510372021
Publisher
Inderalaya : Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya.,
Collation
xviii, 89 hlm. : ilus. ; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
615.707
Content Type
Text
Media Type
unmediated
Carrier Type
unspecified
Edition
-
Subject(s)
Prodi Farmasi
Farmakodinamik
Specific Detail Info
-
Statement of Responsibility
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No other version available

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