Skripsi

PENGARUH EKSTRAK DAUN BELUNTAS (Pluchea indica Less.) SEBAGAI ANTIBAKTERI TERHADAP Porphyromonas gingivalis

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Penilaian

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Introduction: Porphyromonas gingivalis is one of the major etiologies in periodontal diseases. The treatments of periodontal disease are scaling and root planing with adjunct use of mouthwash in order to remove the bacteria causing the periodontal disease. A beluntas leaf (Pluchea indica Less.) has active ingredients such as flavonoids, tannins, saponins and phenols which have been shown to have antibacterial effects. The aim of the study: to determine the effect of beluntas leaves as antibacteria on P. gingivalis. Material and Methods: This in vitro study used 80% ethanol extract of beluntas leaves with the concentration of 30%, 40%, 50%, 60% and 70%. The positive control used 0,2% chlorhexidine gluconate and the negative control was 10% dimethyl sulfoxide (DMSO). The antibacterial test was conducted using disc diffusion method by measuring the diameter of the inhibition zone using a vernier caliper in milimeter, then, the data were analyzed by conducting one way ANOVA and followed by post hoc Tukey test. The Result of the Study: All the concentrations of beluntas leaves extract showed antibacterial activity against P. gingivalis. The inhibition zone diameter of beluntas leaves extract at concentration of 70% was significantly higher compared to other concentrations. However, there was no significant difference between the extract of beluntas leaves group at concentration 70% and the positive control group. Conclusion: The beluntas leaves extract could inhibit the growth of P. gingivalis starting from the concentration of 30% and the highest inhibition zone was at the concentration of 70%. Keywords: antibacterial, beluntas leaves, inhibition zone, Porphyromonas gingivalis.

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Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003217	T50444	T504442021	Central Library (REFERENCES)	Available but not for loan - Not for Loan

Detail Information

Series Title

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Call Number

T504442021

Publisher

Palembang : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya., 2021

Collation

xiii, 53 hlm.; tab.; ilus.; 29 cm.

Language

Indonesia

ISBN/ISSN

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Classification

617.601 07

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Pencegahan Sakit Gigi
Kedokteran Gigi dan Mulut
Ekstrak Daun Beluntas

Specific Detail Info

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Statement of Responsibility

MI

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