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UJI EKSTRAK ETANOL AKAR KAYU KUNING (Arcangelisia flava L. Merr) DALAM MENGHAMBAT ENZIM XANTIN OKSIDASE

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Secondary metabolites that are thought to work as antihyperuricemia are saponins, tannins, flavonoids, terpenoids, and protoberberine alkaloids such as berberine, jatrorizin, and palmatin. In addition, the root of Kayu kuning (Arcangelisia flava (L.) Merr.) contains secondary metabolites such as saponins, tannins, terpenoids, flavonoids, and alkaloids, so it has antihyperuricemic potential. This research was conducted to determine the ability of the ethanol extract of the roots of Kayu kuning (Arcangelisia flava L. Merr) in inhibiting the xanthine oxidase enzyme. This type of research is experimental in vitro using a post-test design. Yellow wood root extraction process by maceration method. Xanthine oxidase inhibition test was carried out using UV-Vis spectrophotometry with 4 concentrations of ethanol extract of yellow wood root and allopurinol used as a comparison. The ethanolic extract of the yellow wood root contains alkaloids, flavonoids, triterpenoids, and quinones. The ethanol extract of Kayu kuning root has an IC50 of 30.4365 ppm and is classified as active in inhibiting the xanthine oxidase enzyme. The ethanolic extract of Kayu kuning root has potential as an antihyperuricemia through the inhibition of the xanthine oxidase enzyme.

Availability
Inventory Code Barcode Call Number Location Status
2107003192T61102T611022021Central Library (Referens)Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T611022021
Publisher
Indralaya : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya.,
Collation
xvii, 43 hlm. : ilus. ; 29 cm
Language
Indonesia
ISBN/ISSN
-
Classification
615.30 7
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Obat-Obat Organik
Prodi Pendidikan Dokter
Specific Detail Info
-
Statement of Responsibility
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No other version available

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