Text

PERBANDINGAN TUMOR INFILTRATING LYMPHOCYTES (TILs) BERDASARKAN KARAKTERISTIK KLINIKOHISTOPATOLOGI PASIEN TUMOR GANAS OVARIUM DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

---

Penilaian

---

Ovarian malignant tumours is a gynecological malignancy with the highest mortality. Immunotherapy, being the main treatment modality, has shown poor efficacy due to the heterogenity of TILs in TME. It is important for us to identify the distribution and density of TILs in TME based on clinicohistopathological characteristics.
This type of research is analytic observational with aapproach cross sectional. The sample of this study was tissue with H&E staining of paraffin block diagnosed as ovarian malignant tumor as the primary data of this study. Secondary data are clinicohistopathological characteristics obtained through medical records. TILs were counted in the stromal and intratumoral areas of ovarian malignant tumor tissue. Then the comparison of TILs density based on clinicohistopathological characteristics was seen.
In this study, the highest incidence of ovarian malignant tumours was found in histopathological features of MOC (25,4%) and HGSC (22.2%), age >45 years (58.7%), late stage (56.7%), tumor size >20 cm (38, 1%), nodule N0 (36.1%), and had close metastases (73%). In this study, there was no significant comparison between TILs in TME and clinicohistopathological characteristics of patients with malignant ovarian tumors (p > 0.05).
The highest incidence of ovarian malignant tumors in this study was found in the histopathological features of MOC dan HGSC, age >45 years, late stage, tumor size >20 cm, nodule N0, and had close metastases. In this study, there was no statistically significant comparison between TILs in TME and the clinicohistopathological characteristics of ovarian malignant tumor patients (p > 0.05).
Ovarian Malignant Tumours, Tumor Infiltrating Lymphocytes, Tumor Microenvironment, Clinicohistopathological Characteristics

---

Availability

Inventory Code	Barcode	Call Number	Location	Status
2107003172	T59678	T596782021	Central Library (Referens)	Available but not for loan - Not for Loan

Detail Information

Series Title

-

Call Number

T596782021

Publisher

Inderalaya : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2021

Collation

xi, 106 hlm. : ilus. ; 29 cm

Language

Indonesia

ISBN/ISSN

-

Classification

616.990 7

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Penyakit Tumor
Prodi Pendidikan Dokter

Specific Detail Info

-

Statement of Responsibility

SEPTA

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment